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healthcare-associated infections (HAI) program

California Antimicrobial Resistance Lab-Epi Alliance

The California Antimicrobial Resistance Lab-Epi Alliance includes clinical and public health laboratorians, infection control practitioners, and epidemiologists working together to address antimicrobial resistance (AR). The goals of the California AR Lab-Epi Alliance are to enhance situational awareness of healthcare-associated AR pathogens, facilitate information and data sharing, and to connect healthcare facilities and laboratories to additional testing resources.

Participants receive updates and join quarterly webinar conferences on AR regional epidemiology and laboratory testing issues resources. To join the California AR Lab-Epi Alliance, please sign up online.

For additional information contact the HAI Program at





Laboratory reporting requirements and healthcare facility recommendations for carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE)

​Carbapenem-resistant Enterobacteriaceae (CRE)

​Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae (CP-CRE): Updated Laboratory Reporting Requirements and Recommendations for Healthcare Facilities - December 11, 2019

Webinar Recording (video will play on YouTube)
Webinar Slides (PDF)

Implementing updated carbapenem breakpoints ​Enterobacteriaceae and Pseudomonas aeruginosa

Implementing Current Breakpoints for Carbapenems and Enterobacteriaceae on Your AST System:  Step by Step Instructions - September 27, 2018*

Webinar Recording (video will play on YouTube)
Webinar Slides (PDF)

*This presentation references supportive materials, tools, and worksheets to assist clinical laboratories with updating breakpoints. Email to obtain copies of these documents.

Carbapenemase testing​CRE and carbapenem-resistant Pseudomonas aeruginosa (CRPA) isolates

​Carbapenemase Testing at the CDPH Microbial Diseases Laboratory: New Tests and Submission Options - November 8, 2017

Webinar Recording (WMV -  Media Player to view)
Webinar Slides (PDF)

Diverse Mechanisms of Resistance in Carbapenem-Resistant Enterobacteriaceae (CRE) in California - June 26, 2018

Webinar Recording (video will play in YouTube)
Webinar Slides (PDF) -  N. Banaei
Webinar Slides (PDF) - S. Bhaurla             

Additional CRE Prevention Strategies information available.

​Colonization testing for carbapenemase-producing CRE (CP-CRE), for example, KPC-producing Klebsiella pneumoniae

​Rectal or fecal swabs

Overview of CDC's New Antibiotic Resistance Laboratory Network – November 15, 2016
Webinar Slides (PDF)

Whole genome sequencing to determine relatedness of isolates​Bacterial isolates when transmission is suspected

Antimicrobial Resistance in California: Updates on Clinical and Public Health Laboratory Testing - November 29th, 2018
Webinar Recording (video will play in YouTube)
Webinar Slides (PDF)

Targeted surveillance to identify pathogens that are difficult to detect​Carbapenem-resistant Acinetobacter baumannii (CRAB), CRPA, and Candida aurisTargeted Surveillance  (PDF)

Description of targeted surveillance goals and objectives, types of testing performed and submission details

mcr-positive Enterobacteriaceae

Cephalasporin-resistant E. coli and Klebsiella

mcr-1 and Detecting Colistin Resistance – March 21, 2017
Webinar slides (PDF)


Candida auris identification, confirmation, and colonization testing

Candida auris

Candida auris: Emergence, Laboratory Information, and Public Health Response - June 27, 2017
Webinar Recording (WMV - Media Player to view)
Webinar Slides (PDF)

Update on Candida auris in California - June 24th, 2019
Webinar Recording (video will play in YouTube)
Webinar Slides (PDF) (will be posted)

Additional CDPH Candida auris information available.

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