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microbial diseases laboratory

Test Order - Modified Carbapenem Inhibition Method

Pre-Approval Required:

Isolates must be confirmed as Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Klebsiella aerogenes , Enterobacter species or Pseudomonas aeruginosa. At this time, acceptance of requests for testing of other Enterobacterales organisms is on a case by case basis after consultation with HAI program at HAIprogram@cdph.ca.gov or MDL points of contact listed below. Isolates of Enterobacterales, other than those listed above, that are submitted without prior consultation will not be tested.

Supplemental Information or Form:

Form LAB AST
MDL Expanded Carbapenemase Testing Frequently Asked Questions (FAQ) (May 2021)

Performed on Specimens From:

Human sources

Acceptable Sample/Specimen Type for Testing:

Isolates must be confirmed as Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Klebsiella aerogenes , Enterobacter  species or Pseudomonas aeruginosa. At this time, acceptance of requests for testing of other Enterobacterales organisms is on a case by case basis after consultation with HAI program at HAIprogram@cdph.ca.gov or MDL points of contact listed below. Isolates of Enterobacterales , other than those listed above, that are submitted without prior consultation will not be tested. If an isolate is positive for a known carbapenemase gene by a molecular method, the mCIM will not be performed.

Minimum Volume Required:

None

Storage & Preservation of Sample/Specimen Prior to Shipping:

Store at ambient temperature.

Transport:

Ship cultures on nonselective nutrient or similar agar in tubes with leak-proof screw cap closures.

Sample/Specimen Labeling:

Two patient identifiers on the specimen container and on the test requisition are required.

Shipping Instructions, Including Specimen Handling Requirements:

Ship at ambient temperature.

Test Methodology:

Phenotypic testing

Turnaround Time:

14 days

Interferences & Limitations:

The results of the mCIM are for epidemiological purposes, and are not intended to guide or monitor treatment for carbapenem resistant bacterial infections.

Additional Information:

None

MDL Points of Contact:

Email: MDL.Submissions@CDPH.ca.gov
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